2-Amino-4-(ethoxycarbonyl)-1,3-thiazole hydrobromide

2-Amino-4-(ethoxycarbonyl)-1,3-thiazole hydrobromide - Names and Identifiers

Name	4-Thiazolecarboxylic acid, 2-amino-, ethyl ester, monohydrobromide
Synonyms	AKOS BBV-000509 ETHYL-2-AMINOTHIAZOLE-4-CARBOXYLIC ACID 4-THIAZOLECARBOXYLIC ACID, 2-AMINO-, ETHYL ESTER 2-Amino-4-(ethoxycarbonyl)-1,3-thiazole hydrobromide 2-Aminothiazole-4-carboxylic acid ethyl ester hydrobromide 2-Amino-4-thiazolecarboxylic acid ethyl ester hydrobromide 2-Aminothiazole-4-carboxylic acid ethyl ester monohydrobromide 4-Thiazolecarboxylic acid, 2-amino-, ethyl ester, hydrobromide 4-Thiazolecarboxylic acid, 2-amino-, ethyl ester, monohydrobromide
CAS	127942-30-7

2-Amino-4-(ethoxycarbonyl)-1,3-thiazole hydrobromide - Physico-chemical Properties

Molecular Formula	C6H8N2O2S
Molar Mass	253.12
Storage Condition	Sealed in dry,Room Temperature

2-Amino-4-(ethoxycarbonyl)-1,3-thiazole hydrobromide - Introduction

Ethyl 2-amino-4-thiazolecarboxylate hydrobromic acid (abbreviated as ATAB) is an organic compound with the following properties and uses:

Nature:
-Appearance: White crystalline solid
-Molecular formula: C6H9BrN2O2S
-Molecular weight: 236.12g/mol
-Solubility: insoluble in water, soluble in organic solvents such as ethanol and acetone

Use:
- ATAB is commonly used in the preparation of other drugs or drug intermediates, such as acetyl azole, thiazoline and 4-hydroxy-2-aminothiazole.
-It can also be used as a meso agent in chiral synthesis.

Preparation Method:
- ATAB is mainly obtained by the esterification reaction of 4-fluoro-2-aminothiazole and glycolic acid.
-Specific reaction steps:
1. Esterification of 4-fluoro -2-aminothiazole under alkaline conditions to generate 4-fluoro -2-(ethyl acetate) thiazole.
2. react with hydrobromic acid under acidic conditions to generate 2-amino -4-thiazolecarboxylic acid ethyl ester hydrobromic acid.

Safety Information:
-The use and handling of ATABs should follow routine laboratory safety practices.
-It is a potentially toxic organic substance and should be avoided by inhalation, skin contamination and ingestion.
-Wear appropriate protective gloves, goggles and lab coats to ensure a fully ventilated work environment.
-If you come into contact with skin, rinse immediately with plenty of water. If you feel unwell, seek medical help.
-During storage and handling, keep ATABs away from ignition and oxidizing agents to avoid the risk of fire or explosion.

Last Update：2024-04-09 15:17:51